メチシリン耐性黄色ブドウ球菌(MRSA )
ブラックシードには、MRSAの臨床分離株に対して、抗菌作用があります。
細かい情報へ
Anti bacterial activity of Nigella sativa
against clinical isolates of methicillin resistant Staphylococcus aureus.
Hannan A1, Saleem S, Chaudhary S, Barkaat M, Arshad MU.
Abstract
BACKGROUND:
Methicillin resistant Staphylococcus aureus
(MRSA) continues to be one of the commonest pathogens encountered in clinical
as well as laboratory practice. It has become a major health problem worldwide.
Newer antimicrobials/agents are urgently needed to combat this problem MRSA
resistance to various anti-staphylococcal agents. In the back-drop of this
difficult situation Nigella sativa commonly known as black seed (ethanolic
extract) was aimed at to evaluate if it had any anti-staphylococcal activity.
METHODS:
The extract was prepared by reflux extraction
method. Disc diffusion and in agar dilution methods were performed to assess
the antibacterial activity. Staphylococcus aureus ATCC 25923 was used as the
standard reference strain.
RESULTS:
All tested strains of MRSA were sensitive to
N. sativa extract at a concentration of 4 mg/disc while the extract had an MIC
range of 0.2-0.5 mg/ml.
CONCLUSION:
The results indicated that N. sativa has
inhibitory effect on MRSA. This finding warrants necessity of further
investigation of this product of folk medicine.
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